The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Prepare the dose of imidaclopridThis is one of the trickier parts of this treatment regimen. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease. Background: Lynxacarus radovskyi has been observed in cats in Malaysia; previously treatment with fipronil and moxidectin/imidacloprid spot-on has been described. Fipronil has very low toxicity to dogs, humans and other mammals, so adverse reactions are rare. Objectives: To compare the efficacy of two spot-on treatments of moxidectin/imidacloprid, two weeks apart to a single oral dose of fluralaner against Lynxacarus radovskyi and evaluate time to re-infestation. advantus™ should only be given to dogs. Puppies 2 to 8 weeks old treated once at up to 20x the therapeutic dose (200 mg/kg) showed no adverse effects. Advantage Multi ® for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Do not give more than one tablet per day. Find helpful customer reviews and review ratings for Advantus (imidacloprid) Oral Dog Flea Treatment, Soft Flea Chews for Dogs 23-110 lbs, 30 doses at Amazon.com. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Information contained on this site pertains only to the United States of America, and is not intended to provide adequate information for product use. Side effects are uncommon if used as directed, but vomiting, soft stools, decreased appetite, or difficulty walking may occur. If you have any questions about flea treatment or medical problems associated with flea infestations, consult your veterinarian. Bayer Healthcare LLC, Animal Health Division, Shawnee Mission, KS 66201 USA, Bayer (reg’d), the Bayer Cross (reg’d) and advantus™ are registered trademarks of Bayer. Contact your veterinarian if you have any questions about flea infestations on your dog. Questions/Comments? In mammals, the primary effects following acute high-dose oral exposure to imidacloprid are mortality, transient cholinergic effects (dizziness, apathy, locomotor effects, … Store at room temperature between 68°F and 77°F (20°C and 25°C) and protect from light. Is there advantus® for cats? For additional information for reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Within days, larvae hatch from these eggs and live undetected in your dog’s surroundings, such as in the carpet and bedding. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Available for Android and iOS devices. IMOXI ™ Topical Solution for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. ● advantus™ has not been tested in pregnant or nursing dogs. Side effects of fipronil and when to report them. Regulations for product use are established by country. Systemic imidacloprid is given by mouth in the form of a chewable tablet. A weekly topical administration of 5x the therapeutic dose … Side effects are uncommon but may include vomiting, soft stools, decreased appetite, or difficulty walking. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Do not use combination products in young pets. Maximal efficacy of all 3 dosages (99.1 to 100%) was observed at 7 days after treatment. Call Bayer at 1-800-255-6826. If a negative reaction occurs, please call your veterinary office. If a negative reaction occurs, please call your veterinary office. Use: advantus™ kills adult fleas and is indicated for the treatment of flea infestations on dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater. Never give your dog two doses at once or give extra doses. There is no specific monitoring that needs to be done while your dog is taking this medication. The adult dosage for most cats is 0.4 mL of the imidacloprid oil. Do not use this medication in cats. This is especially the case if your dog is sick or already debilitated from an illness. Certain combination products should be used in cats. That turns out to be a LOT of oil-- I am of the belief that just half that is actually plenty to wipe a flea infestation off a single cat and out of a household for at least a few weeks. Imidacloprid is moderately toxic if ingested. We’re committed to keeping clients and staff safe during COVID-19 with NEW admittance and check-out processes. Use the syringe provided to ensure accuracy of dosing to the nearest 0.1 mL. Lufenuron is an FDA-approved medication given by mouth in the form of a tablet, liquid, or injection (cats only) to treat flea infestations. 1. Oral imidacloprid should not be used in puppies younger than 10 weeks of age or weighing less than 4 pounds, or in pregnant or lactating dogs. advantus ® (imidacloprid) 37.5mg 30 ct (large dogs; 23-110 lbs.) (7.5 mg/kg) body weight once daily for seven consecutive days. Read honest and unbiased product reviews from our users. Active Ingredients. Product Use Spot-on insecticide for flea control in dogs and cats. In animals, midazolam is given as a sedative. advantus™ contains 7.5 mg or 37.5 mg of imidacloprid. Use cautiously in debilitated and geriatric dogs. Results: All 3 imidacloprid dosages provided flea control > or = 96.9% one day after treatment. ● advantus™ starts to kill fleas within 1 hour. Adult female fleas feed by ingesting blood from your dog and lay eggs that drop off from your dog’s coat. The following diagram illustrates the flea’s life cycle and where advantus™ works: Fleas reproduce rapidly. The capsule is easy to give to your dog and may be given as an occasional dose when you see fleas on your pet or daily if necessary. Results of a chronic feeding study revealed no adverse effects in dogs given imidacloprid at a dose … Imidacloprid has a wide safety margin in mammals, due to a significantly lower affinity to the nicotinic receptors of vertebrates than those of insects. Frontline Plus Flea and Tick Control for Cats and Kittens. This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow. 2,19 In mice, LD 50 values were estimated at 130 mg/kg for males and 170 mg/kg for females. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. The dose of imidacloprid is based on the weight of the dog. Dosage schedule for cats: The recommended minimum doses are 10 mg/kg bodyweight imidacloprid and 1.0 mg/kg bodyweight moxidectin, equivalent to 0.1 ml/kg bodyweight Advocate for cats. Oral dosage forms require careful pharmaceutical formulation. Do not use in pets that are allergic to it. Fleas in your dog’s environment can re-infest your dog. Frontline Plus Flea is the most popular … Because advantus™ does not have an effect on fleas in the environment, your dog may become re-infested with fleas. ● Contact your veterinarian if your dog ingests more than the recommended dose of advantus™. A single female flea may produce up to 2,000 eggs over her lifetime. Flea control with 3.75 mg of imidacloprid/kg of body weight ranged from 94.4 to 96.9% for days 14 to 28 and decreased to 91.6% by 34 days after treatment. Other Names Imidacloprid, benzyl alcohol This SDS covers the following six products: Advantage for Kittens and Small Cats up to 4kg Advantage for Cats over 4kg Advantage for Puppies and Small Dogs up to 4 kg Advantage for Dogs 4-10kg Advantage for Dogs 10-25kg Advocate for cats contains 100 mg/ml imidacloprid and 10 mg/ml moxidectin. Imidacloprid and its nitrosoimine metabolite (WAK 3839) have been well studied in rats, mice and dogs. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Updated: 2020-12-31. A single dose kills adult fleas on your dog. If a negative reaction occurs, please call your veterinary office. As specified in the following table, administer the entire contents of the Advantage Multi® for Catstube that correctly corresponds with the body weight of the cat. 5 Cats receiving oral mirtazapine at 1.88 mg q24h and 3.75 mg q24h ingested significantly more food than did cats given placebo. The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration. ● advantus™ does not protect against ticks or mosquitoes. Select one or more newsletters to continue. Imidacloprid is an insecticide and therefore can cause toxicity in your dog. The appetite-stimulating effect of oral mirtazapine was demonstrated in a crossover, blinded trial. Oral. Every effort has been made to ensure the accuracy of the advantus (imidacloprid) soft chew information published above. Advantage Multi ® for Cats (10 % imidacloprid + 1 % moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Weight of cat [kg] Pipette size to be used Volume [ml] Imidacloprid [mg/kg bw] Give the missed dose as soon as you remember, and then wait the recommended amount of time between doses. Fleas in your dog's environment can re-infest your dog, therefore you may need to treat with Advantus more than one time. When these new fleas are seen on your dog, treat with advantus™. Treat all pets in your household with a flea protection product. Directions: You should weigh your dog before giving this medication to make sure you are using the right size for your dog. Contributors: Rania Gollakner, BS, DVM, MPH. The following is a guideline for typical use of the drug in cats and must not replace your veterinarian’s advice for your individual pet. Small dogs can also be at risk of developing toxicity to imidacloprid. Eggs hatch and may grow into adults in only three weeks. Before using or dispensing any product, read and carefully observe the label directions. To report side effects, call Bayer Veterinary Services at 1-800-422-9874. Moxidectin topical is applied to the skin and is commonly used to prevent heartworms and to treat topical and intestinal parasites. If they are not available, follow their directions in contacting an emergency facility. Start to kill adult fleas within 1 hour. Advantus over the counter soft chews contain Imidacloprid, an insect neurotoxin that works to paralyze and kill fleas within an hour of administration and can be used daily if needed. There are no drug interactions reported at this time. (imidacloprid) soft chew. Your veterinarian may monitor your pet to be sure that the medication is working. Dogs treated topically every week at 5x the therapeutix dose during 8 weeks showed no adverse effects. Rinse syringe between doses. Your dog should be weighed prior to administering this medication to ensure the correct dose. As a general rule, dogs and cats tolerate imidacloprid very well. advantus™ contains 7.5 mg or 37.5 mg of imidacloprid. ©Copyright VCA Hospitals all rights reserved. Disadvantages of the oral route of administration include the relatively slow onset of action, the possibilities of irregular absorption, the destruction of acid-labile drugs in the stomach, and the unsuitability of this route for many high-molecular-weight drugs. It has also been used off label to treat adult heartworms. ● advantus™ may be used together with other products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos. It's hugely important to get make sure that your dog gets exactly the right dose of medicine, at the correct time intervals. * Cats over 18 lbs. While generally safe and effective when prescribed by a veterinarian, midazolam can cause side effects in some animals. Dog medications dosage requirements are generally calculated by weight and measured in mg of medicine per pound of body weight. Therefore, you may need to treat with advantus™ more than one time. Side effects are uncommon but may include irritation at the application site, or, if the medication is accidentally ingested, drooling, shaking, vomiting, and decreased appetite. A review of side effects reported in Australia between 1996 and 2003 found that the most common side effect of using fipronil for dogs was skin irritation or hair loss at the application site. Imidacloprid is given by mouth to treat flea infestations in dogs only. If a negative reaction occurs, please call your veterinary office. Veterinarians usually prescribe clindamycin for cats in a dosage of 5 to 10 mg per pound of the cats body weight every 24 hours.. Three dosages of 24 µg/kg were also highly effective, providing ≥ … The easy-to-use Veraflox ® dispenser makes accurate dosing simple. Description. Cats treated once topically at 8x and 24x the therapeutic dose showed no adverse effects. Serious side effects that could indicate an allergic reaction include noisy breathing, collapse, or pale gums. Advantus Soft Chews are flavored, and may be fed easily by hand. Fipronil is used topically to treat flea, tick, and chewing lice infestations. Use the table to find the right dose for your dog: To give advantus™, place the soft chew directly in your dog’s mouth or allow your dog to take the soft chew from your hand. Uses of Midazolam for Dogs and Cats. The treatment schedule should be based on the local epidemiological situation. 7.5 mg Advantus Soft Chews contain 7.5 mg imidacloprid per chew for dogs … — 85274422 advantus ® has an expiration date you can find on the product label near the barcode. 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