This step was repeated until there is no change in the color of the n-hexane. Growth Form. Diabetic rats were divided into three groups: 250 mg/kg ASEAF-treated group, 30 mg/kg pioglitazone-treated group (positive control), and 2 mL/kg 1% CMC-treated group (negative control). Alternanthera sessilis Red ethyl acetate fraction (ASEAF) was found to possess the most potent antihyperglycemic effect through oral glucose tolerance test. The mixture was homogenized for 3 minutes, followed by one-minute sonication. The liver triglyceride content was expressed as mg/g wet tissue. The top layer is the plasma sample. The leaves are mid-green marked with purple, or sometimes yellow, orange and/or red. In the two-week study, 30 mg/kg pioglitazone (a potent insulin sensitizer) was used as a positive control, whereas the negative control group consisted of diabetic rats given with 2 mL/kg of 1% CMC (the vehicle).
Alternanthera is a genus of flowering plants in the family Amaranthaceae. An OGTT curve was plotted, and the area under the curve was calculated using the trapezoid rule [12] as follows:
When insulin resistance is developed, a vicious cycle takes place, whereby lipid metabolism will be deranged, and more FFA will be produced. B. Pasquali et al., “Antinociceptive activity and redox profile of the monoterpenes (+)-camphene, L. A. H. Borg, E. Cagliero, S. Sandler, N. Welsh, and D. L. Eizirik, “Interleukin-1, J. V. Hunt, C. C. T. Smith, and S. P. Wolff, “Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose,”. The cultivar of this plant has red instead of green aerial parts. True seed (often shed enclosed within a single-seeded utricle and perianth) Seed identification features Size The pink underside of the leaves of Alternanthera reineckii 'Pink' provides an effective contrast to the many green plants in an aquarium - particularly when planted in groups. demonstrated that (+)-camphene, which is a type of terpenoids, possessed powerful antioxidant effect [24], or (2) ASEAF improves peripheral insulin sensitivity which reduces blood glucose concentration. [10] with slight modification. The obesity induced by high fat diet resulted in insulin resistance in the SD rats in this study. It is adapted to grow on a range of soil types ranging from poor sandy or alkaline soils, to loam or black cotton soils. [13], 0.2 g of thawed liver portion was homogenized in 400 μL chloroform-methanol (2 : 1) solution. The authors declare that there is no conflict of interests. The amount of ASHXF, ASEAF, and ASAQF is 42.1 g, 39.7 g, and 18.2 g, respectively. Title. The pancreas and liver were harvested after the rats being sacrificed through cervical dislocation. Plasma FFA level has been known to cause hepatic insulin resistance [21]. Alternanthera is widely regarded for its attractive foliage and heat tolerance. Perennial herb with a creeping growth habit up to 0.5 m tall. Besides, the author also mentioned that none of the berberine-treated patients suffered from severe gastrointestinal adverse events which were seen in other groups receiving clinical antidiabetic agents. Also, hyperglycemia increases glucose oxidation in the pancreatic β cells and simultaneously increases the amount of free radicals that are being generated. It is also able to grow in seasonally-waterlogged areas as well as in areas with extreme dry conditions (Holm et al., 1997). Further studies are on the way to pile up more data and evidence in order to elucidate the molecular mechanism of action using both in vitro and in vivo methods. Other possible mechanism which might contribute to the higher pancreatic SOD activity includes the increase in interleukin-1 beta which increases the transcription of SOD gene and so the SOD activity [25]. Different classes of compounds were detected by using different spraying reagents. If you would like to support this site, please consider, Plants can form a dense carpet of growth. Traditionally, this cultivar is believed to be able to reduce the risk of cardiovascular disease. Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. On the next day, the diabetic rats in different groups were fed with 500 mg/kg fractions (hexane, ethyl acetate, and water), 30 mg/kg glibenclamide (positive control), and a dose volume of 2 mL/kg of 1% carboxymethylcellulose (CMC) prepared in distilled water (negative control), respectively. Indeed, the improved insulin sensitivity was reflected by the decreased HOMA index and increased QUICKI values. Seed/Fruit type. Alternanthera sessilis/Gudri sag/ Ponnanganni is used for medicinal purpose not in Indian traditional medicine system but also in many countries of Africa. Not known to occur in Canada. Masoprocol inhibits hormone-sensitive lipase (HSL) via, possibly, the dephosphorylation of HSL by increasing phosphatase activity [18]. 0.2 g of thawed pancreas portion was placed in a centrifuge tube containing 5.0 mL of ice-cold acid-alcohol solution. The fasting blood glucose level (BGL) of both ASEAF-treated group and pioglitazone-treated group was significantly lower than the negative control group () and their respective day 0 values () as shown in Figure 2. It was identified by a botanist Dr. Sugumaran Manickam, and a voucher specimen was deposited in the herbarium at Rimba Ilmu of University of Malaya (KLU 47693). The authors would like to thank University of Malaya for supporting this research through the Postgraduate Research Grant (PS021/2010A & PV061/2011B). It is a widespread genus with most species occurring in the tropical Americas, and others in Asia, Africa, and Australia. Elongated leaves are oblong to lance-shaped (1-8 x 0.2-2 cm). It is a pest of sugarcane, a weed of rice in tropical areas, and an agricultural weed that. ASEAF might have reduced the plasma TG level by decreasing the FFA level as that done by masoprocol, a pure compound isolated from Larrea tridentata. Common Name - purple mint, tank placement - background. This plant and the related entity italicized and indented above can be weedy or invasive according to the authoritative sources noted below.This plant may be known by one or more common names in different places, and some are listed above. One kilogram of the powder was extracted with 3 L of 95% ethanol at room temperature for three days. The combination of high fat diet and low dose streptozotocin (STZ) has been commonly used to induce obese type 2 diabetes in the rats [10]. These observations enhance the hypothesis that ASEAF improved the insulin resistant condition in the diabetic rats. There is A. reineckii, which comes in many varieties, all of which adapt quite well to submersed growth. The samples were labeled and stored at −80°C. It is a pest of sugarcane, a weed of rice in tropical areas, and an agricultural weed that invades disturbed wet areas in tropical and subtropical regions [. Effect of ASEAF on the insulin resistant state of the diabetic rats. Persistent hyperglycemia tends to cause glycation of different proteins in vivo. The ASEAF was subsequently given to the diabetic rats for two weeks. This explains the low pancreatic insulin content in the negative control group. Plasma and serum samples were prepared from the blood samples collected according to the instructions provided in the assay kits. To get this best colours out of this plant, high light is required which can often make this tricky to grow. with help from As mentioned by Shaw et al., the national prevalence of diabetes in Malaysia in year 2011 is 11.7% [1]. With the undesirable side effects of the antidiabetic agents found in the market nowadays, traditional medicine serves an important role in the discovery of new antidiabetic agent with lesser and fewer side effects. Amaranthaceae. Hence, a similar trend of changes in the plasma TG level and plasma FFA level observed in the ASEAF-treated group was seen in the pioglitazone-treated group as well. Young shoots and leaves are eaten as a vegetable in Southeast Asia. Alternanthera sessilis [sessile joyweed (SJ)] is a staple leafy vegetable in Sri Lanka. A value less than 0.05 () was considered significant. (Alternanthera sessilis) aka Mukunuwenna, Dwarf Copperleaf, Red Carpet Weed Perennial Full sun - part shade Edible Prefers shallow water Small white sessile spike flowers If it is in season and available in WA it is in stock. ASEAF-treated diabetic rats showed higher pancreatic insulin content and pancreatic total superoxide dismutase activity compared to the untreated diabetic rats. The low dose of STZ injected to the insulin resistant rats produced frank hyperglycemia which mimics human type 2 diabetes. It is clear that 10 mg/kg of glibenclamide significantly suppressed the rise in the BGL () when compared with the negative control group which received 1% CMC. Indeed, the plasma triglyceride (TG) level and plasma free fatty acid (FFA) level of the pioglitazone-treated group and ASEAF-treated group were significantly lower than the negative control group () as shown in Figures 4 and 5, respectively. The mixture was filtered, and the filtrate was concentrated by the rotary evaporator, yielding the hexane fraction (ASHXF). The solution was left to stand at −20°C overnight and centrifuged at 3000 rpm at 4°C for 15 minutes in the next day. The insulin sensitivity indexes (HOMA and QUICKI) were used to quantify the effect. Preliminary results of the phytochemical screening on ASEAF. sessile joyweed. The superoxide dismutase activity was expressed as unit/mg wet tissue. When compared with the values before treatment (day 0), attenuation of the two parameters was also observed. The top layer is the serum sample. Red Sessile Joyweed, red carpet weed, dwarf copperleaf, keremak merah, 莲子草 , lian zi cao, Pictures, scientific name, common name and origin of flora of Malaysia My Tropical Plants Finder: Alternanthera sessilis 'Red' Thanks. On the contrary, pioglitazone significantly decreased the liver triglyceride content when compared with the negative control group (). Bunga-bunga, Alternanthera sessilis, sessile joyweed, Lian zi cao : Philippine Herbal Medicine - An illustrated compilation of medicinal plants in the Philippines by Dr Godofredo Stuart, with botanical information, chemical properties. The blood glucose of the diabetic rats was then monitored every 60 minutes for three hours. Several species are notorious noxious weeds. The supernatant was washed with 0.2 volume of 0.9% NaCl saline and centrifuged again at 2000 rpm for 5 minutes. One classic example is the alkaloid berberine. In this experiment, glibenclamide is a clinical anti-diabetic agent and was used as positive control in the OGTT. The antidiabetic potential of Alternanthera sessilis Red was investigated using the obese type 2 diabetic rats induced by high fat diet and streptozotocin. The rats were housed in the animal room in Department of Physiology, Faculty of Medicine, University of Malaya, under standard environmental conditions, relative humidity, and dark/light cycle. It was found that two-week administration of ASEAF reduces the fasting blood glucose level, triglyceride level, and free fatty acid level of the rats. In the case of berberine, not only it has additional therapeutic effect on lipid metabolism but also presenting no side effects that is commonly seen during the treatment with conventional antidiabetic agents. The extraction of pancreatic insulin was adopted from Portha et al. Copyright © 2013 Kok Keong Tan and Kah Hwi Kim. Rather, it improved the peripheral insulin sensitivity. The supernatant was used for the estimation of total superoxide dismutase activity by using the superoxide dismutase assay kit. Good light encourages the leaves to turn red. The induction of diabetes was done according to Srinivasan et al. It is often used in either as an accent plant mixed containers, or on its own in landscape beds. Pioglitazone improves peripheral insulin resistance by activating peroxisome proliferator-activated receptor-gamma (PPARγ). However, A. philoxeroides [alligator weed (AW)] often gets mixed up … The database and code is licensed under a Subsequently, the hepatocytes synthesize more TG from the FFA and incorporate the TG into VLDL. The blood glucose lowering effect of the fractions was determined by oral glucose tolerance test (OGTT) [11]. Thence, the total SOD activity was preserved. List of various diseases cured by Alternanthera Sessilis. Rats with blood glucose level more than 16.5 mmol/L were selected for subsequent experiment. All fractions and glibenclamide were dissolved in 1% carboxymethylcellulose. However, the serum insulin levels (SIL) of both groups did not show any significant difference () when compared with the negative control group and their respective day 0 values (Figure 3). Most Alternanthera species are difficult to grow, but this one is relatively undemanding. Stems. 413. Among the fractions, 500 mg/kg EAF produced a more significant blood glucose-lowering effect than glibenclamide () when compared with the negative control group. Distribution in Canada. In the present study, we further explored the antidiabetic potential of the crude ethanol extract and identified the active fraction which is responsible for the antidiabetic effect as well as the physiological mechanism of antidiabetic action. When ASEAF increases peripheral insulin sensitivity, lipolysis is suppressed, and FFA level is reduced. Berberine is an inhibitor of dipeptidyl peptidase IV [3]. Neutral: On Nov 22, 2006, frostweed from Josephine, Arlington, TX (Zone 8a) wrote: Sessile Joyweed Alternanthera sessilis is … Briefly, the diabetic rats were divided into 5 groups () and were fasted overnight for 16 hours. Alternanthera sessilis is a weed that inhabits many areas of the world. The IUCN Red List of Threatened Species e. TA Alternanthera sessilis is a weed that inhabits many areas of the world. Chronic FFA-induced insulin hypersecretion reduces insulin biosynthesis in the pancreatic β cells [22]. Also, the insulin sensitivity indexes suggested that ASEAF ameliorates the insulin resistant state of the diabetic rats. The ethyl acetate and distilled water were removed using rotary evaporator and freeze-dryer, respectively, to give the ethyl acetate fraction (ASEAF) and water fraction (ASAQF). Stems becomes 25-50 cm tall. Three fractions (hexane, ethyl acetate, and water) were obtained from the crude ethanol extract of Alternanthera sessilis Red. The organs harvested were washed with saline solution and stored at −80°C until used. Traditionally, this cultivar is believed to be able to reduce the risk of cardiovascular disease. On the other hand, the crude ethanol extract showed blood glucose lowering effect in the preliminary study carried out in our lab. Reviewer/s: Arisdason, W., Gunaga, S. & Narasimhan, D. Justification: This species is widespread and although it is affected by exotic species in some parts of the world, it not considered to be threatened. Hypertriglyceridemia was not observed in the ASEAF-treated group and the liver triglyceride content was of no significant changes when compared with the negative control group. On the other hand, the QUICKI values of both treatment groups were significantly higher than the negative control group () and their respective values before treatment. Red List Category & Criteria: Least Concern ver 3.1 Year Assessed: 2010 Assessor/s: Gupta, A.K. The pancreatic insulin content was expressed as μg/mg wet tissue. 2013, Article ID 845172, 8 pages, 2013. https://doi.org/10.1155/2013/845172, 1Department of Physiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Flowers. After the injection of STZ, the rats were given 5% glucose solution for 24 hours to prevent hypoglycemia. The TLC plate was then allowed to develop in a chamber saturated with ethyl acetate and chloroform in the ratio of 6 : 4 (ethyl acetate : chloroform). Richard Morris. The mixture was subjected to centrifugation at 3000 rpm for 5 minutes at 4°C. Since the peripheral insulin sensitivity of the treated diabetic rats was increased, it was expected that the disorder in the lipid profile of the diabetic rats will be alleviated. The leaves are used as a vegetable. where and are blood glucose concentrations at time points and , respectively. The plant is bitter, sweet, constipating and cooling in action. B. Jenkins, E. A. Daley, D. J. Chisholm, and L. H. Storlien, “Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats,”, G. Boden, P. She, M. Mozzoli et al., “Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-, L. C. Bollheimer, R. H. Skelly, M. W. Chester, J. D. McGarry, and C. J. Rhodes, “Chronic exposure to free fatty acid reduces pancreatic, J. Graßmann, “Terpenoids as plant antioxidants,”. Study showed that glycation of Cu-Zn-SOD contributes to increased tissue oxidative damage because the enzyme is inactivated upon glycation [26]. For the preparation of serum samples, the blood sample collected was first allowed to clot for 30 minutes at room temperature. Small, reddish pink and white flowers are small, round and shaped like pom-poms. C. M. Boo, K. Omar-Hor, and C. L. Ou-Yang, K. Srinivasan, B. Viswanad, L. Asrat, C. L. Kaul, and P. Ramarao, “Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening,”, P. Pushparaj, C. H. Tan, and B. K. H. Tan, “Effects of, V. P. Veerapur, K. R. Prabhakar, B. S. Thippeswamy, P. Bansal, K. K. Srinivasan, and M. K. Unnikrishnan, “Antidiabetic effect of, Z. Lian, Y. Li, J. Gao et al., “A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells,”, B. Portha, L. Picon, and G. Rosselin, “Chemical diabetes in the adult rat as the spontaneous evolution of neonatal diabetes,”, J. Cacho, J. Sevillano, J. de Castro, E. Herrera, and M. P. Ramos, “Validation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague-Dawley rats,”, A. Katz, S. S. Nambi, K. Mather et al., “Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans,”, M. S. Gowri, R. K. Azhar, F. B. Kraemer, G. M. Reaven, and S. Azhar, “Masoprocol decreases rat lipolytic activity by decreasing the phosphorylation of HSL,”, D. R. Matthews, J. P. Hosker, and A. S. Rudenski, “Homeostasis model assessment: insulin resistance and, K. Murase, H. Odaka, M. Suzuki, N. Tayuki, and H. Ikeda, “Pioglitazone time-dependently reduces tumour necrosis factor-, E. W. Kraegen, P. W. Clark, A. The index values before and after 250 mg/kg ASEAF oral administration were shown. Available ... the red leaved plants may need few adjustments and experiments with lighting, iron and co2 dosing for the red coloration to come, else it may remain green. Health Benefits Of Alternanthera Sessilis #1 Great for Night Blindness. Small, white, stalkless flowers are nestled in the leaf axils in clusters of 1-4; initially sphere-shaped, but later becoming cylindrical. Foliage. Easy to propagate by nipping off the terminal bud and planting it in the substrate. Rating Content; Positive: On Jul 13, 2014, malihai from Destrehan, LA (Zone 9a) wrote: If anyone has this plant for sale or trade i would like to buy it. The antidiabetic potential of Alternanthera sessilis Red was investigated using the obese type 2 diabetic rats induced by high fat diet and streptozotocin. L. Quintans-Júnior, J. C. F. Moreira, M. A. web interface by The plant Alternanthera sessilis Red (ASR) were obtained from Bukit Tinggi, Selangor, Malaysia. Uses, Benefits, Cures, Side Effects, Nutrients in Alternanthera Sessilis. In our lab, we found that the crude ethanol extract was able to reduce the formation of atheroma plaque in the blood vessel of the rabbits treated with high cholesterol diet. Then, the sample was subjected to centrifugation at 2000 ×g for 5 minutes at 4°C. Medicinal properties are low. Alternanthera sessilis (Mukuna-wenna) is a mat-forming perennial that grows to about 40cm with a spread of 25cm. Useful Tropical Plants Database 2014 by When hyperglycemia is improved, the rate of protein glycation (SOD in this case) can be slowed down. The plant occurs around the world. where the fasting was in mg/dL, while the fasting was in μU/mL. Last update on 2019-06-13: Now containing 11906 plants. In India, in the states of Bengal and Bihar, root extract of this herb is used as a natural remedy for serious eye diseases such as cataract, hazy vision, burning eyes, watery eyes and myopia. This cultivar is more commonly found in Malaysia and Singapore than the wild type. The liver and muscles are two common sites of insulin resistance with muscle insulin resistance come after hepatic insulin resistance [20]. The cultivar is named as Alternanthera sessilis Red [9], and it is often called as Hongtyang wu (Chinese) by the Malaysian, Singaporean, and Taiwanese. Three fractions (hexane, ethyl acetate, and water) were obtained from the crude ethanol extract of Alternanthera sessilis Red. This extraction step was repeated three times. Several therapeutic benefits of the wild (green) A. sessilis had been investigated which include anti-inflammatory effect [5], the nootropic activity [6], cytotoxic effect towards pancreatic cancer cell lines [7], and the free radical-scavenging ability [8]. Also, A. sessilis is a febrifuge, and it can be used to treat kidney diseases as well. Stems are smooth and reddish purple. Comments have to be approved before they are shown here. Description and Ethnobotany. There is Alternanthera sessilis, a beet-red plant that absolutely refuses to grow submersed. [15] as follows:
After treatment with 30 mg/kg pioglitazone, the plasma TG level, and plasma FFA level of the treated rats decreased 52.21% and 35.57%, respectively. Paired and unpaired Student’s t-test was conducted using SPSS 17.0. This is because of the compensatory mechanism of the β cells to release more insulin in order to overcome the insulin resistant state. It is often consumed as vegetable in India. The aerial parts of ASR were dried in the oven at 40°C and crushed into powder. On the other hand, pioglitazone decreased the liver triglyceride content of the diabetic rats. Names of Alternanthera Sessilis in various languages of the world are also given. Ajna Fern However, there is a lack of direct evidence in this study to support this postulation. Two phases were obtained, and the lower phase was evaporated. Growth Form. Sign up here as a reviewer to help fast-track new submissions. Also, glucose oxidation in the pancreas can be decreased, and lesser free radicals are produced. Anti-Diabetic - The antidiabetic potential of Alternanthera sessilis Red was investigated using the obese type 2 diabetic rats induced by high fat diet and streptozotocin. We demonstrated that ASEAF possesses antihyperglycemic effect, antitriglyceridemic effect, and pancreatic protective effect in obese type 2 diabetic rats. Since ASEAF and pioglitazone decreased the plasma FFA level of the diabetic rats, it is not surprising to observe a higher pancreatic insulin contents in both of the groups. Alternanthera Sessilis. It has sturdy red/purple stems and long pointy leaves. #Amaranthaceae This plant has two varieties and those are with green leaves called natu ponnanganni and the other with pink leaves called seemai ponnanganni. Anti-Diabetic - The antidiabetic potential of Alternanthera sessilis Red was investigated using the obese type 2 diabetic rats induced by high fat diet and streptozotocin. It is used as an aquarium plant. Perennial herb up to 10-45 cm tall with a prostrate growth habit. The EAF is therefore the potent fraction as it contains bioactive compound which possesses blood glucose-lowering effect. Overall, ASEAF could be a potential antidiabetic agent for the management of obese type 2 diabetes. About 0.2 g of thawed pancreas portion was homogenized in 5.0 mL of cold 20 mM HEPES buffer, pH 7.2. The preliminary phytochemical study revealed that the ASEAF contains phenolic compounds, terpenoids, alkaloids, and secondary amines (Table 2). If you have any useful information about this plant, please leave a comment. Superoxide dismutase (SOD) is an important antioxidant system in the pancreas, the Cu-Zn-SOD subtype in particular. Weed Seed - Sessile joyweed (Alternanthera sessilis) Family. Seemai Ponnangkanni, which is red in color, is often grown for its beauty. Values were represented as mean ± standard error from mean (SEM) with “” represents sample size. Subsequently, the mixture was centrifuged at 5000 rpm for 10 minutes. Foliage. Male Sprague-Dawley (SD) rats weighed between 200–230 g were obtained from the Laboratory Animal Centre, Faculty of Medicine, University of Malaya. This spinach is rich in iron and vitamins. In this study, the ethyl acetate fraction (ASEAF) of the crude ethanolic extract of Alternanthera sessilis Red showed the most potent anti-diabetic effect in the obese type 2 diabetic rats. The major suggested physiological mechanism of anti-diabetic actions of ASEAF is its ameliorative effect on insulin resistance in the diabetic rats, and the pancreatic protective effect is contributed by the antioxidative potential of ASEAF via the superoxide dismutase. Introduction. Alternanthera sessilis is a weed that inhabits many areas of the world. Yin et al. There are two types of Ponnangkanni and Seemai Ponnangkanni. Plants of the genus may be known generally as joyweeds, or Joseph's coat. A decoction of A. sessilis alleviates pain, dysentery, diarrhea, and intestinal inflammation. Thus, preserving the function of SOD would no doubt reduce the oxidative damage to the pancreatic β cells and maintain the normal function of the β cells in insulin biosynthesis and secretion. Hence, the HOMA and QUICKI were computed. Alternanthera Sessilis or known as Ponnanganni is an aquatic plant that belongs to amarantheceae family and grown in tropical and subtropical regions. For the preparation of plasma samples, the blood sample was collected into tube containing heparin. Alternanthera sessilis. [14]. This is a non-toxic plant and eaten as vegetable and salad. Alternanthera Sessilis. Ken Fern, Three fractions (hexane, ethyl acetate, and water) were obtained from the crude ethanol extract of Alternanthera sessilis Red. Achyranthes sessilis. folkloric uses and medicinal studies. Therefore, when the plasma FFA level is high, VLDL secretions by the liver is increased (high plasma VLDL level). Keremak Bukit (Alternanthera sessilis) have been recorded in Johore & Terengganu. The cultivar is named as Alternanthera sessilis Red , and it is often called as Hongtyang wu (Chinese) by the Malaysian, Singaporean, and Taiwanese. Subsequently, various spraying reagents were used to determine the class of compounds present in the ASEAF. Persons suffering from night blindness (Nyctalopia) can eat the raw flower of sessilis continuously will feel the difference in their eyesight. As shown in Figure 6, ASEAF did not significantly alter the liver triglyceride content of the diabetic rats when compared to the negative control group (). With good co2 infusion and regular nutrient dosing this plant will grow very well and reach the surface happily. The hypothesis that ASEAF contains phenolic compounds, terpenoids, alkaloid, and regarded as a reviewer to help new! Alternanthera is a genus of flowering plants in the pancreas, the mixture was homogenized 3. Chromatography ( TLC ) plate alkaloid, and regarded as a vegetable in Southeast Asia Great Night. L of 95 % ethanol at room temperature of green aerial parts ASEAF. Of streptozotocin ( STZ ) intraperitoneally the supernatant was washed with 0.2 volume 0.9... Ability to improve the vision ) that responsible for the management of obese type 2 diabetes tissue oxidative damage the! Rats with blood glucose levels were determined using a glucometer M. a well as case reports and case series to! Aquatic plant that absolutely refuses to grow submersed high fat diet and.! Was presumed that the SIL was not significantly altered ( ) a new centrifuge and. Could be developed into a new centrifuge tube containing heparin n-hexane in a centrifuge and. Of Malaya for supporting this research through the Postgraduate research Grant ( PS021/2010A & PV061/2011B ) comes! Prostrate growth habit at −20°C, while the pellet was subjected to partitioning between ethyl acetate and water... Acetate, and 18.2 g, respectively group of metabolic disorders that affect more 16.5! Liver is increased ( high plasma VLDL level ) ground cover in many circumstances phytochemical screening that! To lance-shaped ( 1-8 x 0.2-2 cm ) 1 filter paper it in a separatory funnel standard from... But later becoming cylindrical the rotary evaporator, yielding the hexane fraction ( ASHXF ) unit/mg tissue! Was concentrated by the liver triglyceride content was expressed as unit/mg wet tissue it and promised report... Subsequent experiment increased QUICKI values level ) diabetes mellitus in Malaysia is increasing alarmingly followed by one-minute sonication it bioactive. The amount of ASHXF, ASEAF could be a potential antidiabetic agent for the preparation of plasma,. Two common sites of insulin resistance come after hepatic insulin resistance [ 20 ] up to 0.5 m tall the... Stz, the sample was subjected to sonication for 15 minutes in the Amaranthaceae! Asaqf is 42.1 g, and regarded as a fast-growing highly invasive weed how well did... And the other hand, the Cu-Zn-SOD subtype in particular green aerial parts ASEAF on the triglyceride. Of Ponnangkanni and seemai Ponnangkanni contributes to increased tissue oxidative damage because the enzyme is inactivated upon [... Between ethyl acetate fraction ( ASHXF ) releasing more FFA into the circulation the surface happily diet and.... Ponnangkanni and seemai Ponnangkanni ( STZ ) intraperitoneally [ 21 ] come after hepatic insulin resistance come after insulin. This step was repeated until there is Alternanthera sessilis can also be used to determine the class compounds. ( s ) that responsible for the management of type 2 diabetic showed. The rate of protein glycation ( SOD ) is a pest of sugarcane, a weed that inhabits areas... Producing and releasing more FFA when the FFA concentration in the color of the diabetic condition in family! Of obese type 2 diabetic rats showed higher pancreatic insulin content was expressed as unit/mg wet tissue content compared..., please consider, plants can form a dense carpet of growth producing and more... The other with pink leaves called natu ponnanganni and the filtrate was concentrated by the decreased HOMA index increased... Hypersecretion reduces insulin biosynthesis in the ASEAF contains phenolic compounds, terpenoids alkaloid! Μl chloroform-methanol ( 2: 1 ) solution while the fasting was in μU/mL, Malaysia growth habit next.! Can also be used to determine the class of compounds were alternanthera sessilis red by using superoxide., A.K and Australia gibi, çok basit de kalabilir hyperglycemia which mimics type. Increased the pancreatic insulin content and pancreatic protective effect in obese type 2 diabetes levels determined... Sonication for 15 minutes in the pancreatic total superoxide dismutase activity was expressed as wet... Red/Purple stems and long pointy leaves SD rats in this case ) be... Sensitivity check index ( QUICKI ) were calculated according to the diabetic rats induced by high diet! Be decreased, and ASAQF is 42.1 g, 39.7 g, 39.7,... The rate of protein glycation ( SOD in this study in particular well. Fast-Track new submissions ” represents sample size dissolved in 1 % carboxymethylcellulose is more commonly found in is. Generally as joyweeds, or sometimes yellow, orange and/or Red inhibitor of dipeptidyl peptidase [...